Contrave is a FDA approved weight loss medication for overweight and obese patients. Contrave works by reducing hunger and controlling cravings. When combined with healthy diet and exercise it results in a 5%-10% decrease in overall weight on average. It is approved for patients with other risk factors such as high blood pressure, high cholesterol, or diabetes making it a more suitable choice. Contrave starts as a once a day pill approved to help lose weight and keep it off.